導(dǎo)師簡(jiǎn)介
姓名：暢雪麗 性別：女 政治面貌：中共黨員
學(xué)歷：研究生 學(xué)位：博士 職稱：副主任醫(yī)師
博、碩導(dǎo)師：碩導(dǎo) 本崗位工作年數(shù)：10年
研究方向：神經(jīng)肌肉病
榮譽(yù)稱號(hào)：無(wú)
學(xué)術(shù)任職：山西省醫(yī)學(xué)會(huì)神經(jīng)病學(xué)分會(huì)青年委員會(huì)副主任委員；山西省醫(yī)學(xué)會(huì)神經(jīng)病學(xué)分會(huì)神經(jīng)肌肉病學(xué)組副組長(zhǎng)
近五年承擔(dān)科研課題情況：
國(guó)家自然科學(xué)基金青年項(xiàng)目， 項(xiàng)目名稱：NEMF參與神經(jīng)發(fā)育致神經(jīng)變性疾病發(fā)生的分子機(jī)制研究，項(xiàng)目編號(hào)：82001222
中華國(guó)際醫(yī)學(xué)交流基金會(huì)創(chuàng)新思維研究基金，項(xiàng)目名稱：MELAS患者神經(jīng)元中PPAR/PGC-1α通路的關(guān)鍵作用及干預(yù)研究，項(xiàng)目編號(hào)：Z-2016-20-1801
山西省青年科技研究基金面上青年基金項(xiàng)目， 項(xiàng)目名稱：AMPK介導(dǎo)的能量代謝重構(gòu)在線粒體腦肌病作用機(jī)制的初步研究，項(xiàng)目編號(hào)：201801D221415
代表性論著及近五年的代表性論文（限10項(xiàng)以內(nèi)）：
通訊作者. Wei Zhang, Jing Ma, Jiaying Shi, Shan Huang, Rongjuan Zhao, Xiaomin Pang, Juan Wang, Junhong Guo, Xueli Chang*, GGC repeat expansions in NOTCH2NLC causing a phenotype of lower motor neuron syndrome. J Neurol, 2022, 269(8):4469-4477.
第一作者. Xueli Chang, Zhaoxu Yin, Wei Zhang, Jiaying Shi, Chuanqiang Pu, Qiang Shi, Juan Wang, Jing Zhang, Li Yan, Wenqu Yang, Junhong Guo*, Data-independent acquisition-based quantitative proteomic analysis of m.3243A>G MELAS reveals novel potential pathogenesis and therapeutic targets. Medicine (Baltimore), 2022, 101(41):e30938.
通訊作者. Li Yan, Zhao-Xu Yin, Xue-Li Chang*, Rui Wang, Xiu-Min Zhang, Jun-Hong Guo. Neuromuscular junction disorders: Experimental models and pathophysiological mechanisms. Acta Neurobiol Exp (Wars), 2022;82(4):501-510.
第一作者. Chang X, Wu Y, Zhou J, Meng H, Zhang W, Guo J*, A meta-analysis and systematic review of Leigh syndrome: clinical manifestations, respiratory chain enzyme complex deficiency, and gene mutations. Medicine (Baltimore), 2020, 99(5): e18634.
通訊作者. Wen Q, Chang X*, Guo J*, A childhood?onset nemaline myopathy caused by novel heterozygote variants in the nebulin gene with literature review. Acta Neurologica Belgica, 2020,120(6):1351-1360.
教學(xué)科研
