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導(dǎo)師簡介

姓名：李常新  性別：女    政治面貌：中共黨員

學(xué)歷：研究生   學(xué)位：博士   職稱：主任醫(yī)師      

博、碩導(dǎo)師：博士研究生導(dǎo)師   本崗位工作年數(shù)：36年

研究方向：腦血管病基礎(chǔ)與臨床

榮譽(yù)稱號(hào)：2021年山西醫(yī)科大學(xué)第一醫(yī)院優(yōu)秀共產(chǎn)黨員

學(xué)術(shù)任職：山西省神經(jīng)內(nèi)科質(zhì)量控制中心主任，中國卒中學(xué)會(huì)醫(yī)療質(zhì)量管理與促進(jìn)分會(huì)常務(wù)委員，中國醫(yī)師協(xié)會(huì)神經(jīng)病學(xué)分會(huì)腦血管病專業(yè)委員會(huì)委員，山西省醫(yī)師協(xié)會(huì)老年醫(yī)師分會(huì)神經(jīng)病學(xué)專業(yè)委員會(huì)主任委員，山西省老年醫(yī)學(xué)學(xué)會(huì)神經(jīng)醫(yī)學(xué)分會(huì)會(huì)長，山西省醫(yī)學(xué)會(huì)腦血管病專業(yè)委員會(huì)副主任委員。

近五年承擔(dān)科研課題情況：

1. 2017年山西省科學(xué)技術(shù)廳應(yīng)用基礎(chǔ)研究項(xiàng)目，項(xiàng)目名稱：HTRA1錯(cuò)義突變和基因多態(tài)性在遺傳性腦小血管病種致病作用，項(xiàng)目編號(hào)：201701D121173

2. 2021年山西省衛(wèi)生健康委科研項(xiàng)目，項(xiàng)目名稱：雜合HTRA1基因錯(cuò)義突變（c.905G>A，p.Arg302Gln）在bEnd.3細(xì)胞中的分子機(jī)制研究，項(xiàng)目編號(hào)：2020080  

3. 2021年山西省基礎(chǔ)研究計(jì)劃項(xiàng)目（自由探索類）自然科學(xué)研究面上項(xiàng)目，項(xiàng)目名稱：HTRA1基因下調(diào)與過表達(dá)對(duì)小鼠腦微血管內(nèi)皮細(xì)胞功能影響的研究，項(xiàng)目編號(hào): 202103021224404

   代表性論著及近五年的代表性論文（限10項(xiàng)以內(nèi)）：

4. Xu SY, Li HJ, Li S, Ren QQ, Liang JL, Li CX*. Heterozygous Pathogenic and Likely Pathogenic Symptomatic HTRA1 Variant Carriers in Cerebral Small Vessel Disease. Int J Gen Med. 2023 Mar 29;16:1149-1162.

5. Xu SY, Li L, Sun WX, Shen JY, Li CX*. Case report: Hypnic headache responds to agomelatine-a potential prophylactic treatment option. Front Neurol. 2023 Jun 23;14:1179391.

6. Xu SY, Song MM, Li L, Li CX*. Adie's Pupil: A Diagnostic Challenge for the Physician. Med Sci Monit. 2022 Mar 8;28:e934657.

7. Xu SuiYi, Li HuiJuan, Huang Jing, Li XiuPing, Li ChangXin*. Migraine with Brainstem Aura Accompanied by Disorders of Consciousness.[J]. Journal of pain research,2021,14.

8. Xu SuiYi, Song MaoMei, Liu DongYuan, Li ChangXin*, Xue LiXi, Li Yang. Contrast-induced encephalopathy with significantly elevated levels of cerebrospinal fluid protein. [J]. British journal of neurosurgery,2021.

9. Xu SuiYi, Wang RuoJun, Zhang Lei, Li ChangXin*. Basilar dolichoectasia with intermural hematoma accompanied by cerebral microbleeds and white matter hyperintensities: A case report. [J]. Medicine,2021,100(33).

10. Sui-yi Xu*, Chang-xin Li*, Le-yi Li, Yu Song, Yi Sui. Wallerian degeneration of bilateral cerebral peduncles after acute carbon monoxide poisoning[J]. BMC Neurology, 2020, 20(49).

11. Sui-Yi Xu, Ze-Xing Li, Xiao-Wei Wu, Ling Li, Chang-Xin Li*. Frequency and Pathophysiology of Post-Seizure Todd’s Paralysis[J]. Medical Science Monitor,2020,26.

12. Xu SY, Xi F C , Wu X W, Li C X*.  Ischemic stroke in the combined territories of the septum pellucidum and the cingulate gyrus: A case report and literature review. Medicine (Baltimore). 2019;98(23):e15879.

13. Xiaowei Wu, Changxin Li*, Jinming Mao, Ling Li, Yan Liu, Yao Hou. Heterozygous HTRA1 missense mutation in CADASIL-like family disease. Braz J Med Biol Res. 2018; 51(5): e6632.