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導(dǎo)師簡介

姓名：王宏勤 性別：男 政治面貌：中共黨員

學(xué)歷：研究生 學(xué)位：博士 職稱：教授

博、碩導(dǎo)師：博導(dǎo)      本崗位工作年數(shù)：30年

研究方向：腦腫瘤、腦血管疾病基礎(chǔ)與臨床

榮譽稱號：山西省首批“三晉英才”-拔尖骨干人才，山西省首批學(xué)術(shù)技術(shù)帶頭人，第一完成人獲得山西省科技進(jìn)步獎二等獎1項，山西省高?？萍歼M(jìn)步獎一等獎1項。

學(xué)術(shù)任職：山西醫(yī)科大學(xué)神經(jīng)外科碩導(dǎo)、博導(dǎo)，國家衛(wèi)生健康委能力提升和繼續(xù)教育神經(jīng)外科專家委員會委員，山西省醫(yī)學(xué)會神經(jīng)外科專業(yè)委員會侯任主任委員，中國醫(yī)師協(xié)會神經(jīng)外科分會全國委員

近五年承擔(dān)科研課題情況：

國家自然基金面上項目-MicroRNA-195 在人腦膠質(zhì)瘤替莫唑胺化療耐藥中的作用及機制研究（81470115）

代表性論著及近五年的代表性論文（限10項以內(nèi)）

1. Radiotherapy combined with anti-CEACAM1 immunotherapy to induce survival advantage in glioma.Discov Oncol. 2023 Mar 16;14(1):32.

2. MicroRNA-195 reverses the resistance to temozolomide through targeting cyclin E1 in glioma cells. Anticancer Drugs. 2019 Jan;30(1):81-88.

3. ANXA2 is a potential biomarker for cancer prognosis and immune infiltration: A systematic pan-cancer analysis.Front Genet. 2023 Jan 12;14:1108167.

4. Different changes in granulocyte-colony stimulating factor and its correlation with inflammatory biomarkers in patients after traumatic brain injury.Neuroreport. 2020 Mar 4;31(4):293-299.

5. Reduced expression of microRNA-497 is associated with greater angiogenesis and poor prognosis in human gliomas. Hum Pathol. 2016 Dec;58:47-53.

6. Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma.Oncol Lett. 2018 Mar;15(3):3496-3503.

7. Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1.Curr Pharm Des. 2013;19(35):6382-9.

8. p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.Mol Med Rep. 2015 Jun;11(6):4165-73.

9. Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Results in Durable Therapeutic Efficacy in Mice with Intracranial Gliomas. Med Sci Monit. 2017 Jul 24;23:3593-3602.

10. The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injury. J Surg Res. 2013 Oct;184(2):1006-12.